2 นักวิทย์ผู้พัฒนา “วัคซีน mRNA” ต่อสู้โควิด-19 ซิวโนเบลการแพทย์ 2023

FILE – Japan Prize 2022 laureates Hungarian-American biochemist Katalin Kariko, left, and American physician-scientist Drew Weissman, right, pose with their trophies during the Japan Prize presentation ceremony Wednesday, April 13, 2022, in Tokyo. (AP Photo/Eugene Hoshiko, Pool, File)

2 นักวิทย์ผู้พัฒนา “วัคซีน mRNA” – Thomas Perlmann, secretary of the Nobel Assembly, announces the Nobel Prize in medicine at the Karolinska Institute in Stockholm. The Nobel Prize in medicine has been awarded to Katalin Karikó and Drew Weissman for discoveries that enabled the development of effective mRNA vaccines against COVID-19. (AP)

FILE – Katalin Kariko, speaks after receiving, together with six other scientists, the Princess of Asturias Award for Technical & Scientific Research 2021 from Spain’s Princess of Asturias Leonor, at a ceremony in Oviedo, northern Spain, Friday Oct. 22, 2021. THe Nobel Prize in medicine awarded to Katalin Karikó and Drew Weissman for enabling development of mRNA COVID-19 vaccines , it was announced on Monday, Oct. 2, 2023. (AP Photo/Manu Fernandez, File)

2 นักวิทย์ผู้พัฒนา “วัคซีน mRNA” – Figure 1. Methods for vaccine production before the COVID-19 pandemic. © The Nobel Committee for Physiology or Medicine. Ill. Mattias Karlén

Figure 2. mRNA contains four different bases, abbreviated A, U, G, and C. The Nobel Laureates discovered that base-modified mRNA can be used to block activation of inflammatory reactions (secretion of signaling molecules) and increase protein production when mRNA is delivered to cells. © The Nobel Committee for Physiology or Medicine. Ill. Mattias Karlén